Description
Cancer is a major public health and economic issue and its burden is ever increasing. Only in the US, it accounts for $90 Billion in direct medical costs. It costs $2.7 Billion to develop a cancer…
Summary
- Cancer is a major public health and economic issue and its burden is ever increasing.
- Many drugs will fail simply because they are effective only on a subset of cancers, which was not initially recognized at the time of the trial” Multi-Omics Patterns For Clinical Variable Modelling One way to eliminate these problems is to accept that clinical variables, such as drug response, are driven by genome/transcriptome/epigenome patterns and not just by mutations of single genes.
- Once we accept that, we have to have efficient methods for analyzing multilevel data sets, such as multi-omics, from cancer biopsies or tumor models.
- In addition, 2) we can model variables such as survival and drug response.